The South Baranof Wilderness is a federally designated wilderness area within the Tongass National Forest, located on Baranof Island, Alaska. Covering 319,568 acres south of Sitka, the South Baranof protects glacier-carved fjords, hanging valleys, old-growth temperate rainforests and sheer granite mountains.

The wilderness was created by Congress in 1980 as part of the Alaska National Interest Lands Conservation Act.